A set of training materials for professionals working in intervention epidemiology, public health microbiology and infection control and hospital hygiene.
Need help with your investigation or report writing? Ask the Expert. Free advice from the professional community.
You can't make decissions on this page's approval status because you have not the owner or an admin on this page's Group.
Schistosomes are known to survive intravascularly for many years despite the continuing antiparasite immune response by the infected host. The living schistosomes are capable to reduce surface antigenicity and develop a tegument resistant to immune damage. In addition to this 'camouflage-behavior', these parasites influence cellular immune response using "chemical defenses":
Epidermal Langerhans cells (LCs) are a specific kind of antigen presenting cells and play a key role in immune defense mechanisms and in numerous immunological disorders. Studies have shown that percutaneous infection of mice with the helminth parasite Schistosoma mansoni leads to the activation of LCs but also to their retention in the epidermis. Moreover parasites transiently impair the departure of LCs from the epidermis and their subsequent accumulation as dendritic cells in the draining lymph nodes. The inhibitory effect is mediated by soluble lipophilic factors released by the parasites and not by host-derived antiinflammatory cytokines, such as interleukin-10.
Join the discussion about this article in the forum!
Marion Muehlen posted on 9/29/2015 11:53:51 AM:there is an error/typo in table 5. The risk % in the reference group should be 20,0% and not 29,0%.
katrine borgen replied on 9/30/2015 2:25:54 PM: Table 8 is wrong: Column title "cases exposed" is erroneous, as the N include all cases, not only those who ate i.e. potato salad. Also the table title reads "Dummy table for food specific attack rates in a case-control study". In a case controls study you don't calculate attack rates.
You need to be logged in to post comments.
You can log in here. You can register here if you haven't done so yet.